AJP - Renal Physiology -- Table of Contents (November 1 2004, 287 [5])

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ESSAYS ON APS CLASSIC PAPERS:

Hershel Raff, Dale Benos, and Margaret Reich: Editorial Introduction to the classic papers commemorating the APS Legacy Project
Am J Physiol Renal Physiol 287: F859-F860, 2004; doi:10.1152/classicessays.00001.2004 [Full Text] [PDF]

James A. Schafer: Editorial Focus Experimental validation of the countercurrent model of urinary concentration
Am J Physiol Renal Physiol 287: F861-F863, 2004; doi:10.1152/classicessays.00020.2004 [Abstract] [Full Text] [PDF]

Gerhard Giebisch: Editorial Focus Two classic papers in acid-base physiology: contributions of R. F. Pitts, R. S. Alexander, and W. D. Lotspeich
Am J Physiol Renal Physiol 287: F864-F865, 2004; doi:10.1152/classicessays.00005.2004 [Abstract] [Full Text] [PDF]

Jeff M. Sands: Editorial Focus Micropuncture: unlocking the secrets of renal function
Am J Physiol Renal Physiol 287: F866-F867, 2004; doi:10.1152/classicessays.00019.2004 [Abstract] [Full Text] [PDF]

T. H. Hostetter and T. W. Meyer: Editorial Focus The development of clearance methods for measurement of glomerular filtration and tubular reabsorption
Am J Physiol Renal Physiol 287: F868-F870, 2004; doi:10.1152/classicessays.00009.2004 [Abstract] [Full Text] [PDF]

EDITORIAL FOCUS:

Dietmar Kültz: Hypertonicity and TonEBP promote development of the renal concentrating system
Am J Physiol Renal Physiol 287: F876-F877, 2004; doi:10.1152/ajprenal.00272.2004 [Full Text] [PDF]

Ki-Hwan Han, Seung Kyoon Woo, Wan-Young Kim, Soo-Hyun Park, Jung-Ho Cha, Jin Kim, and H. Moo Kwon: Maturation of TonEBP expression in developing rat kidney
Am J Physiol Renal Physiol 287: F878-F885, 2004. First published June 29, 2004; doi:10.1152/ajprenal.00047.2004 [Abstract] [Full Text] [PDF]

INVITED REVIEWS:

Jürg Biber, Serge M. Gisler, Nati Hernando, Carsten A. Wagner, and Heini Murer: PDZ interactions and proximal tubular phosphate reabsorption
Am J Physiol Renal Physiol 287: F871-F875, 2004; doi:10.1152/ajprenal.00244.2004 [Abstract] [Full Text] [PDF]

ARTICLES:

Jing Wu, Yahua Zhang, Nanping Wang, Linda Davis, Guangrui Yang, Xian Wang, Yi Zhu, Matthew D. Breyer, and Youfei Guan: Liver X receptor- ${alpha}$ mediates cholesterol efflux in glomerular mesangial cells
Am J Physiol Renal Physiol 287: F886-F895, 2004. First published July 27, 2004; doi:10.1152/ajprenal.00123.2004 [Abstract] [Full Text] [PDF]

Li E. Yang, Arvid B. Maunsbach, Patrick K. K. Leong, and Alicia A. McDonough: Differential traffic of proximal tubule Na⁺ transporters during hypertension or PTH: NHE3 to base of microvilli vs. NaPi2 to endosomes
Am J Physiol Renal Physiol 287: F896-F906, 2004. First published July 20, 2004; doi:10.1152/ajprenal.00160.2004 [Abstract] [Full Text] [PDF]

S. Adler and H. Huang: Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase
Am J Physiol Renal Physiol 287: F907-F913, 2004; doi:10.1152/ajprenal.00060.2004 [Abstract] [Full Text] [PDF]

Ping Li, Houli Jiang, LiMing Yang, Shuo Quan, Sandra Dinocca, Francisca Rodriguez, Nader G. Abraham, and Alberto Nasjletti: Angiotensin II induces carbon monoxide production in the perfused kidney: relationship to protein kinase C activation
Am J Physiol Renal Physiol 287: F914-F920, 2004. First published July 13, 2004; doi:10.1152/ajprenal.00073.2004 [Abstract] [Full Text] [PDF]

Meghna Trivedi, Vihang A. Narkar, Tahir Hussain, and Mustafa F. Lokhandwala: Dopamine recruits D_1A receptors to Na-K-ATPase-rich caveolar plasma membranes in rat renal proximal tubules
Am J Physiol Renal Physiol 287: F921-F931, 2004. First published July 20, 2004; doi:10.1152/ajprenal.00023.2004 [Abstract] [Full Text] [PDF]

Naomi Niisato, Douglas C. Eaton, and Yoshinori Marunaka: Involvement of cytosolic Cl^– in osmoregulation of ${alpha}$ -ENaC gene expression
Am J Physiol Renal Physiol 287: F932-F939, 2004. First published August 3, 2004; doi:10.1152/ajprenal.00131.2004 [Abstract] [Full Text] [PDF]

Jingfei Cheng, Michael A. Thompson, Henry J. Walker, Catherine E. Gray, Montserrat M. Diaz Encarnacion, Gina M. Warner, and Joseph P. Grande: Differential regulation of mesangial cell mitogenesis by cAMP phosphodiesterase isozymes 3 and 4
Am J Physiol Renal Physiol 287: F940-F953, 2004. First published July 27, 2004; doi:10.1152/ajprenal.00079.2004 [Abstract] [Full Text] [PDF]

Dimin Li, Yuan Wei, and Wen-Hui Wang: Dietary K intake regulates the response of apical K channels to adenosine in the thick ascending limb
Am J Physiol Renal Physiol 287: F954-F959, 2004. First published July 20, 2004; doi:10.1152/ajprenal.00183.2004 [Abstract] [Full Text] [PDF]

Isabelle Runembert, Sylviane Couette, Pierre Federici, Emma Colucci-Guyon, Charles Babinet, Pascale Briand, Gérard Friedlander, and Fabiola Terzi: Recovery of Na-glucose cotransport activity after renal ischemia is impaired in mice lacking vimentin
Am J Physiol Renal Physiol 287: F960-F968, 2004. First published July 6, 2004; doi:10.1152/ajprenal.00064.2004 [Abstract] [Full Text] [PDF]

H. A. Praetorius, J. Praetorius, S. Nielsen, J. Frokiaer, and K. R. Spring: ${beta}$ ₁-Integrins in the primary cilium of MDCK cells potentiate fibronectin-induced Ca²⁺ signaling
Am J Physiol Renal Physiol 287: F969-F978, 2004. First published June 29, 2004; doi:10.1152/ajprenal.00096.2004 [Abstract] [Full Text] [PDF]

Joao Seda Neto, Atsunori Nakao, Kei Kimizuka, Anna Jeanine Romanosky, Donna B. Stolz, Takashi Uchiyama, Michael A. Nalesnik, Leo E. Otterbein, and Noriko Murase: Protection of transplant-induced renal ischemia-reperfusion injury with carbon monoxide
Am J Physiol Renal Physiol 287: F979-F989, 2004. First published August 3, 2004; doi:10.1152/ajprenal.00158.2004 [Abstract] [Full Text] [PDF]

Shenyang Li, Renu Bhatt, Judit Megyesi, Neriman Gokden, Sudhir V. Shah, and Didier Portilla: PPAR- ${alpha}$ ligand ameliorates acute renal failure by reducing cisplatin-induced increased expression of renal endonuclease G
Am J Physiol Renal Physiol 287: F990-F998, 2004. First published July 27, 2004; doi:10.1152/ajprenal.00206.2004 [Abstract] [Full Text] [PDF]

Xiaohong Zhang, Carlotta E. Groves, Andrew Bahn, Wendy M. Barendt, Marcos D. Prado, Matthias Rödiger, Varanuj Chatsudthipong, Gerhard Burckhardt, and Stephen H. Wright: Relative contribution of OAT and OCT transporters to organic electrolyte transport in rabbit proximal tubule
Am J Physiol Renal Physiol 287: F999-F1010, 2004. First published July 13, 2004; doi:10.1152/ajprenal.00156.2004 [Abstract] [Full Text] [PDF]

Pascale H. Lane, Jianhong Sun, Kay Devish, and William J. Langer: Dissociation of renal TGF- ${beta}$ and hypertrophy in female rats with diabetes mellitus
Am J Physiol Renal Physiol 287: F1011-F1020, 2004. First published July 27, 2004; doi:10.1152/ajprenal.00031.2004 [Abstract] [Full Text] [PDF]

S. Soodvilai, V. Chatsudthipong, K. K. Evans, S. H. Wright, and W. H. Dantzler: Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules
Am J Physiol Renal Physiol 287: F1021-F1029, 2004. First published July 6, 2004; doi:10.1152/ajprenal.00080.2004 [Abstract] [Full Text] [PDF]

Gustavo Frindt and Lawrence G. Palmer: Apical potassium channels in the rat connecting tubule
Am J Physiol Renal Physiol 287: F1030-F1037, 2004. First published July 27, 2004; doi:10.1152/ajprenal.00169.2004 [Abstract] [Full Text] [PDF]

N. D. Vaziri and K. Liang: ACAT inhibition reverses LCAT deficiency and improves plasma HDL in chronic renal failure
Am J Physiol Renal Physiol 287: F1038-F1043, 2004. First published July 27, 2004; doi:10.1152/ajprenal.00150.2004 [Abstract] [Full Text] [PDF]

Wei Wang, Amit Mitra, Brian Poole, Sandor Falk, M. Scott Lucia, Shalini Tayal, and Robert Schrier: Endothelial nitric oxide synthase-deficient mice exhibit increased susceptibility to endotoxin-induced acute renal failure
Am J Physiol Renal Physiol 287: F1044-F1048, 2004; doi:10.1152/ajprenal.00136.2004 [Abstract] [Full Text] [PDF]

Jing Dong, Sampath Ramachandiran, Kulbhushan Tikoo, Zhe Jia, Serrine S. Lau, and Terrence J. Monks: EGFR-independent activation of p38 MAPK and EGFR-dependent activation of ERK1/2 are required for ROS-induced renal cell death
Am J Physiol Renal Physiol 287: F1049-F1058, 2004. First published June 29, 2004; doi:10.1152/ajprenal.00132.2004 [Abstract] [Full Text] [PDF]

Rui Pedrosa, Pedro Gomes, Ulrich Hopfer, Pedro A. Jose, and Patrício Soares-da-Silva: G_i ${alpha}$ 3 protein-coupled dopamine D₃ receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular cells is a PLC-PKC-mediated event
Am J Physiol Renal Physiol 287: F1059-F1066, 2004. First published July 20, 2004; doi:10.1152/ajprenal.00139.2004 [Abstract] [Full Text] [PDF]

O. Barbier, G. Jacquillet, M. Tauc, P. Poujeol, and M. Cougnon: Acute study of interaction among cadmium, calcium, and zinc transport along the rat nephron in vivo
Am J Physiol Renal Physiol 287: F1067-F1075, 2004. First published July 27, 2004; doi:10.1152/ajprenal.00120.2004 [Abstract] [Full Text] [PDF]

Jian Song, Xinqun Hu, Osman Khan, Ying Tian, Joseph G. Verbalis, and Carolyn A. Ecelbarger: Increased blood pressure, aldosterone activity, and regional differences in renal ENaC protein during vasopressin escape
Am J Physiol Renal Physiol 287: F1076-F1083, 2004. First published June 29, 2004; doi:10.1152/ajprenal.00075.2004 [Abstract] [Full Text] [PDF]

L. A. Birder, H. Z. Ruan, B. Chopra, Z. Xiang, S. Barrick, C. A. Buffington, J. R. Roppolo, A. P. D. W. Ford, W. C. de Groat, and G. Burnstock: Alterations in P2X and P2Y purinergic receptor expression in urinary bladder from normal cats and cats with interstitial cystitis
Am J Physiol Renal Physiol 287: F1084-F1091, 2004. First published July 13, 2004; doi:10.1152/ajprenal.00118.2004 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover Cover: Image of a 50-µm-thick vibrotome section illustrating immunostaining for L194 in the inner stripe of outer medullary and initial portion of inner medullary rat kidney (IMi). L194 immunoreactivity appears in the terminal portion of the descending thin limb (DTL) of the long loop of Henle and DTL of the short loop of Henle in the IMi, which represents the localization of UT-A2. In these portions, urea transporters have an important role in recycling urea and thus in generating the urea concentration gradient in the deep IM. However, long-term treatment with cyclosporine accompanied by the urine-concentrating deficit decrease UT-A2 expression. Each tubule examined under higher magnification showed decreased immunoreactivity with UT-A2. Reduced expression of this transporter caused by CsA can be attributed to urine-concentrating capacity. Magnification: ×20.