EDITORIAL FOCUS:

Jill W. Verlander

The thiazide-sensitive NaCl cotransporter: a new target for acute regulation of salt and water transport by angiotensin II
Am J Physiol Renal Physiol 293: F660-F661, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00260.2007 [Full Text] [PDF]  

Monica B. Sandberg, Anne D. M. Riquier, Kaarina Pihakaski-Maunsbach, Alicia A. McDonough, and Arvid B. Maunsbach

ANG II provokes acute trafficking of distal tubule Na⁺-Cl^– cotransporter to apical membrane
Am J Physiol Renal Physiol 293: F662-F669, 2007. First published May 16, 2007; doi:10.1152/ajprenal.00064.2007 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Rajiv Agarwal

Relationship between circadian blood pressure variation and circadian protein excretion in CKD
Am J Physiol Renal Physiol 293: F655-F659, 2007. First published June 20, 2007; doi:10.1152/ajprenal.00188.2007 [Abstract] [Full Text] [PDF]  

INVITED REVIEWS:

Leila V. Virkki, Jürg Biber, Heini Murer, and Ian C. Forster

Phosphate transporters: a tale of two solute carrier families
Am J Physiol Renal Physiol 293: F643-F654, 2007. First published June 20, 2007; doi:10.1152/ajprenal.00228.2007 [Abstract] [Full Text] [PDF]  

ARTICLES:

Jesus Dominguez, Pengfei Wu, C. Subah Packer, Constance Temm, and Katherine J. Kelly

Lipotoxic and inflammatory phenotypes in rats with uncontrolled metabolic syndrome and nephropathy
Am J Physiol Renal Physiol 293: F670-F679, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00021.2007 [Abstract] [Full Text] [PDF]  

Yaxi Chen, Xiong Z. Ruan, Qiu Li, Ailong Huang, John F. Moorhead, Stephen H. Powis, and Zac Varghese

Inflammatory cytokines disrupt LDL-receptor feedback regulation and cause statin resistance: a comparative study in human hepatic cells and mesangial cells
Am J Physiol Renal Physiol 293: F680-F687, 2007. First published July 18, 2007; doi:10.1152/ajprenal.00209.2007 [Abstract] [Full Text] [PDF]  

Markus Hörbelt, So-Young Lee, Henry E. Mang, Nicole L. Knipe, Yoshikazu Sado, Andreas Kribben, and Timothy A. Sutton

Acute and chronic microvascular alterations in a mouse model of ischemic acute kidney injury
Am J Physiol Renal Physiol 293: F688-F695, 2007. First published July 11, 2007; doi:10.1152/ajprenal.00452.2006 [Abstract] [Full Text] [PDF]  

Thomas L. Pannabecker and William H. Dantzler

Three-dimensional architecture of collecting ducts, loops of Henle, and blood vessels in the renal papilla
Am J Physiol Renal Physiol 293: F696-F704, 2007. First published July 3, 2007; doi:10.1152/ajprenal.00231.2007 [Abstract] [Full Text] [PDF] [Supplemental Videos]  

Marouan Abouhamed, Natascha A. Wolff, Wing-Kee Lee, Craig P. Smith, and Frank Thévenod

Knockdown of endosomal/lysosomal divalent metal transporter 1 by RNA interference prevents cadmium-metallothionein-1 cytotoxicity in renal proximal tubule cells
Am J Physiol Renal Physiol 293: F705-F712, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00198.2007 [Abstract] [Full Text] [PDF]  

H. Thomas Lee, Mihwa Kim, Minjae Kim, NaLa Kim, Frederic T. Billings, IV, Vivette D. D'Agati, and Charles W. Emala, Sr.

Isoflurane protects against renal ischemia and reperfusion injury and modulates leukocyte infiltration in mice
Am J Physiol Renal Physiol 293: F713-F722, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00161.2007 [Abstract] [Full Text] [PDF]  

Aihua Zhang, Zhanjun Jia, Xiaohua Guo, and Tianxin Yang

Aldosterone induces epithelial-mesenchymal transition via ROS of mitochondrial origin
Am J Physiol Renal Physiol 293: F723-F731, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00480.2006 [Abstract] [Full Text] [PDF]  

Mariona Font-Llitjós, Lídia Feliubadaló, Meritxell Espino, Ramon Clèries, Sandra Mañas, Isabelle M. Frey, Sara Puertas, Guillem Colell, Sergio Palomo, Jessica Aranda, Joana Visa, Manuel Palacín, and Virginia Nunes

Slc7a9 knockout mouse is a good cystinuria model for antilithiasic pharmacological studies
Am J Physiol Renal Physiol 293: F732-F740, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00121.2007 [Abstract] [Full Text] [PDF]  

Kathrin Hochegger, Tobias Schätz, Philipp Eller, Andrea Tagwerker, Dorothea Heininger, Gert Mayer, and Alexander R. Rosenkranz

Role of / and / T cells in renal ischemia-reperfusion injury
Am J Physiol Renal Physiol 293: F741-F747, 2007. First published June 13, 2007; doi:10.1152/ajprenal.00486.2006 [Abstract] [Full Text] [PDF]  

Robert A. Fenton, Lone Brønd, Søren Nielsen, and Jeppe Praetorius

Cellular and subcellular distribution of the type-2 vasopressin receptor in the kidney
Am J Physiol Renal Physiol 293: F748-F760, 2007. First published June 6, 2007; doi:10.1152/ajprenal.00316.2006 [Abstract] [Full Text] [PDF] [Supplemental Methods and Figures]  

Jianning Zhang, Ion Alexandru Bobulescu, Sunita Goyal, Peter S. Aronson, Michel G. Baum, and Orson W. Moe

Characterization of Na⁺/H⁺ exchanger NHE8 in cultured renal epithelial cells
Am J Physiol Renal Physiol 293: F761-F766, 2007. First published June 20, 2007; doi:10.1152/ajprenal.00117.2007 [Abstract] [Full Text] [PDF]  

Alexander Sturm, Valentin Gorboulev, Dmitry Gorbunov, Thorsten Keller, Christopher Volk, Bernhard M. Schmitt, Peter Schlachtbauer, Giuliano Ciarimboli, and Hermann Koepsell

Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity
Am J Physiol Renal Physiol 293: F767-F779, 2007. First published June 13, 2007; doi:10.1152/ajprenal.00106.2007 [Abstract] [Full Text] [PDF]  

Jane Stubbe, Kirsten Madsen, Finn T. Nielsen, Rasmus K. Bonde, Ole Skøtt, and Boye L. Jensen

Postnatal adrenalectomy impairs urinary concentrating ability by increased COX-2 and leads to renal medullary injury
Am J Physiol Renal Physiol 293: F780-F789, 2007. First published June 20, 2007; doi:10.1152/ajprenal.00193.2007 [Abstract] [Full Text] [PDF]  

Jiuan-Miaw Liao, Cho-Hsun Yang, Chen-Li Cheng, Shwu-Fen Pan, Mei-Jung Chen, Pei-Chen Huang, Gin-Den Chen, Kwong-Chung Tung, Hsien-Yu Peng, and Tzer-Bin Lin

Spinal glutamatergic NMDA-dependent cyclic pelvic nerve-to-external urethra sphincter reflex potentiation in anesthetized rats
Am J Physiol Renal Physiol 293: F790-F800, 2007. First published March 20, 2007; doi:10.1152/ajprenal.00296.2006 [Abstract] [Full Text] [PDF]  

Kanishka Mohib, Qiunong Guan, Hong Diao, Caigan Du, and Anthony M. Jevnikar

Proapoptotic activity of indoleamine 2,3-dioxygenase expressed in renal tubular epithelial cells
Am J Physiol Renal Physiol 293: F801-F812, 2007. First published July 3, 2007; doi:10.1152/ajprenal.00044.2007 [Abstract] [Full Text] [PDF]  

Russell F. Husted, Kenneth A. Volk, Rita D. Sigmund, and John B. Stokes

Discordant effects of corticosteroids and expression of subunits on ENaC activity
Am J Physiol Renal Physiol 293: F813-F820, 2007. First published July 3, 2007; doi:10.1152/ajprenal.00225.2007 [Abstract] [Full Text] [PDF]  

Deepa Sankaran, Neda Bankovic-Calic, Malcolm R. Ogborn, Gary Crow, and Harold M. Aukema

Selective COX-2 inhibition markedly slows disease progression and attenuates altered prostanoid production in Han:SPRD-cy rats with inherited kidney disease
Am J Physiol Renal Physiol 293: F821-F830, 2007. First published May 30, 2007; doi:10.1152/ajprenal.00257.2006 [Abstract] [Full Text] [PDF]  

Paul Jennings, Christian Koppelstaetter, Sonia Aydin, Thomas Abberger, Anna Maria Wolf, Gert Mayer, and Walter Pfaller

Cyclosporine A induces senescence in renal tubular epithelial cells
Am J Physiol Renal Physiol 293: F831-F838, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00005.2007 [Abstract] [Full Text] [PDF]  

Liliana Monica Bivol, Rolf Kristian Berge, and Bjarne Magnus Iversen

Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension
Am J Physiol Renal Physiol 293: F839-F845, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00140.2007 [Abstract] [Full Text] [PDF]  

Manfred Andratsch, Elisabeth Feifel, Lynn Taylor, Morgan O'Hayre, Herbert Schramek, Norman P. Curthoys, and Gerhard Gstraunthaler

TGF- signaling and its effect on glutaminase expression in LLC-PK₁-FBPase⁺ cells
Am J Physiol Renal Physiol 293: F846-F853, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00139.2007 [Abstract] [Full Text] [PDF]  

Iram Zafar, Yunxia Tao, Sandor Falk, Kimberly McFann, Robert W. Schrier, and Charles L. Edelstein

Effect of statin and angiotensin-converting enzyme inhibition on structural and hemodynamic alterations in autosomal dominant polycystic kidney disease model
Am J Physiol Renal Physiol 293: F854-F859, 2007. First published June 20, 2007; doi:10.1152/ajprenal.00059.2007 [Abstract] [Full Text] [PDF]  

Øyvind B. Vågnes, Bjarne M. Iversen, and William J. Arendshorst

Short-term ANG II produces renal vasoconstriction independent of TP receptor activation and TxA₂/isoprostane production
Am J Physiol Renal Physiol 293: F860-F867, 2007. First published June 13, 2007; doi:10.1152/ajprenal.00510.2006 [Abstract] [Full Text] [PDF]  

Wusheng Yan, Lynn Spruce, Michael M. Rosenblatt, Thomas R. Kleyman, and Ronald C. Rubenstein

Intracellular trafficking of a polymorphism in the COOH terminus of the -subunit of the human epithelial sodium channel is modulated by casein kinase 1
Am J Physiol Renal Physiol 293: F868-F876, 2007. First published June 27, 2007; doi:10.1152/ajprenal.00194.2007 [Abstract] [Full Text] [PDF]  

Anees Ahmad Banday, Fatima Rizwan Fazili, and Mustafa F. Lokhandwala

Insulin causes renal dopamine D1 receptor desensitization via GRK2-mediated receptor phosphorylation involving phosphatidylinositol 3-kinase and protein kinase C
Am J Physiol Renal Physiol 293: F877-F884, 2007. First published June 13, 2007; doi:10.1152/ajprenal.00184.2007 [Abstract] [Full Text] [PDF]  

Amie Traylor, Thomas Hock, and Nathalie Hill-Kapturczak

Specificity protein 1 and Smad-dependent regulation of human heme oxygenase-1 gene by transforming growth factor-1 in renal epithelial cells
Am J Physiol Renal Physiol 293: F885-F894, 2007. First published June 13, 2007; doi:10.1152/ajprenal.00519.2006 [Abstract] [Full Text] [PDF]  

Susan C. Kiley and Robert L. Chevalier

Species differences in renal Src activity direct EGF receptor regulation in life or death response to EGF
Am J Physiol Renal Physiol 293: F895-F903, 2007. First published July 11, 2007; doi:10.1152/ajprenal.00227.2007 [Abstract] [Full Text] [PDF]  

Jessica A. Martel, Donna Michael, Géza Fejes-Tóth, and Anikó Náray-Fejes-Tóth

Melanophilin, a novel aldosterone-induced gene in mouse cortical collecting duct cells
Am J Physiol Renal Physiol 293: F904-F913, 2007. First published July 3, 2007; doi:10.1152/ajprenal.00365.2006 [Abstract] [Full Text] [PDF]  

Mohammad Asghar, Liza George, and Mustafa F. Lokhandwala

Exercise decreases oxidative stress and inflammation and restores renal dopamine D1 receptor function in old rats
Am J Physiol Renal Physiol 293: F914-F919, 2007. First published July 18, 2007; doi:10.1152/ajprenal.00272.2007 [Abstract] [Full Text] [PDF]  

Izumi Kamo and Tadatoshi Hashimoto

Involvement of reflex urethral closure mechanisms in urethral resistance under momentary stress condition induced by electrical stimulation of rat abdomen
Am J Physiol Renal Physiol 293: F920-F926, 2007. First published July 11, 2007; doi:10.1152/ajprenal.00466.2006 [Abstract] [Full Text] [PDF]  

C. Chassin, M. Bens, J. de Barry, R. Courjaret, J. L. Bossu, F. Cluzeaud, S. Ben Mkaddem, M. Gibert, B. Poulain, M. R. Popoff, and A. Vandewalle

Pore-forming epsilon toxin causes membrane permeabilization and rapid ATP depletion-mediated cell death in renal collecting duct cells
Am J Physiol Renal Physiol 293: F927-F937, 2007. First published June 13, 2007; doi:10.1152/ajprenal.00199.2007 [Abstract] [Full Text] [PDF]  

Hiroyuki Kobori, Yuri Ozawa, Ryousuke Satou, Akemi Katsurada, Kayoko Miyata, Naro Ohashi, Naoki Hase, Yuki Suzaki, Curt D. Sigmund, and L. Gabriel Navar

Kidney-specific enhancement of ANG II stimulates endogenous intrarenal angiotensinogen in gene-targeted mice
Am J Physiol Renal Physiol 293: F938-F945, 2007. First published July 18, 2007; doi:10.1152/ajprenal.00146.2007 [Abstract] [Full Text] [PDF]  

Guerman Molostvov, Sean James, Simon Fletcher, Jeanette Bennett, Hendrik Lehnert, Rosemary Bland, and Daniel Zehnder

Extracellular calcium-sensing receptor is functionally expressed in human artery
Am J Physiol Renal Physiol 293: F946-F955, 2007. First published May 30, 2007; doi:10.1152/ajprenal.00474.2006 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Akemi Katsurada, Yoshiaki Hagiwara, Kazuya Miyashita, Ryousuke Satou, Kayoko Miyata, Naro Ohashi, L. Gabriel Navar, and Hiroyuki Kobori

Novel sandwich ELISA for human angiotensinogen
Am J Physiol Renal Physiol 293: F956-F960, 2007. First published June 6, 2007; doi:10.1152/ajprenal.00090.2007 [Abstract] [Full Text] [PDF]  

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